Working with these two programs greatly reduces the amount of work necessary to generate models, as it is possible to thread a protein primary sequence onto a 3D template and get an immediate feedback of how well the threaded protein will be accepted by the reference structure before submitting a request to build missing loops and refine sidechain packing. Structural Bioinformatics Group at the Biozentrum in Basel. Swiss Institute of Bioinformatics (SIB) at the Swiss-PdbViewer is tightly linked to SWISS-MODEL, an automated homology modeling server developed within the Swiss-PdbViewer (aka DeepView) has been developped since 1994 by Nicolas Guex.
The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts.Īmino acid mutations, H-bonds, angles and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface. Swiss-PdbViewer (aka DeepView) is an application that provides a user friendly interface allowing to analyze several proteins at the same time.
I currently have no plan to update it to run on OSX 10.15įor information, v4.1.1 works up to OSX Mojave (10.14). If you absolutely need it, refrain from updating, boot from an older OSX version, or use the PC version within a virutal machine. Please note that Swiss-PdbViewer is a 32 bits application and will * NOT * run on OSX Catalina
